The 2025-2026 winter season in the USA is coming to an end. The subclade K of Influenza A (H3N2) became the predominant strain, with the highest severity in the pediatric (0-17 y/o) population, resulting in 25 million cases, 330,000 hospitalizations, and 20,000 deaths. COVID-19 peaked in late summer with a 9.2% positivity rate and is currently below 3% nationwide, with low levels. RSV had a lower level of activity this year with onset later than usual, and hospitalizations have remained elevated through April. Respiratory virus panels have expanded revealing more hospital cases of Human Metapneumovirus (hMPV), Parainfluenza virus. and Rhinovirus.

